Read e-book online Air Pollution - Monitoring, Mdlg., Health and Control PDF

By M. Khare

ISBN-10: 9535103814

ISBN-13: 9789535103813

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Diagnosis/medical monitoring cadmium in urine and/or in blood are 50 nmol/l whole blood or 3 nmol/mmol creatinine. Lead in whole blood is a reliable test. Erythrocyte protoporphyrin (EP) test can also be used but it is not sensitive to detect high levels of lead in children. Acute exposure is best measured by mercury in blood and chronic exposure by mercury in urine Comprehensive Comparison of Trace Metal Concentrations in Inhaled Air Samples MetalRoute of exposure NickelInhalation, ingestion - - Health effects 35 Diagnosis/medical monitoring The National Maximum Workplace Concentration Committee (NMWCC) of the Netherlands proposed that urine nickel concentration 40 µg/g creatinine, or serum nickel concentration 5 µg/l (both measured in samples obtained at the end of a working week or a work shift) be considered warning limits for further investigation of workers exposed to nickel metal or soluble nickel compounds.

Its haemolytic activity is due to its ability to cause a fall in erythrocyte-reduced glutathione content. Signs and symptoms of arsine poisoning include haemolysis, which develops after a latent period that is dependent on the intensity of exposure. Inhalation of 250 ppm of arsine gas is instantly lethal. Exposure from 25 to 50 ppm for 30 minutes is lethal, and 10 ppm may be lethal after longer exposures. The signs and symptoms of poisoning are those characteristic of an acute and massive haemolysis.

Pulmonary absorption of inhaled respirable cadmium dust is estimated at 20 to 50%. After absorption via the gastrointestinal tract or the lung, cadmium is transported to the liver, where production of a cadmium-binding lowmolecular-weight protein, metallothionein, is initiated (61). About 80 to 90% of the total amount of cadmium in the body is considered to be bound to metallothionein. This prevents the free cadmium ions from exerting their toxic effects. It is likely that small amounts of metallothionein-bound cadmium are constantly leaving the liver and being transported to the kidney via the blood.

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Air Pollution - Monitoring, Mdlg., Health and Control by M. Khare

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